Most studies reveal that relative risk of myocardial infarction exceeds 5 to 8 times compared to general population.4 Studies have shown that the prevalence of dyslipidemia in lupus patients ranges from 36% at diagnosis to 60% or even higher after 3 years.5 Patients with SLE have an elevated plasma TG, LDL- C, Apoprotein B, and decreased HDL-C.6 Elevated TG levels in SLE patients are in part attributable to anti-lipoprotein lipase (anti-LPL), which are present in 47% of patients.7 The gene discussed is LPL; the disease is metabolic syndrome.