XDH and heart failure: The purpose of this study was to perform a meta metaanalysis to evaluate the evidence supporting SUA as a predictor of all-cause mortality in patients with heart failure (HF) The Higher uric acid level was associated with long-term adverse outcomes in these patients.12 Several researchers have shown a correlation between increased serum uric acid levels in CHF and morbidity and mortality.11,13,14 which, in turn, increases XO activity and subsequently SUA levels.