S100A8 and infection: In developing countries prevalence of H. pylori infection may exceed as compared to developed countries where 20-50% are affected with infection.1 Previous studies suggest that H. pylori is genetically variable and certain genotypes are only detected in certain populations.2 Several virulence factors of H. pylori strain, such as babA2, cagA, vacA, and iceA1have been identified and involved in pathogenesis of infection.3