R gene-mediated resistance is typically qualitative and effective to restrict pathogen strains carrying specific effectors (avirulence proteins, Avr); in absence of a successful R-Avr interaction, however, quantitative disease resistance reduces the growth and spread of virulent pathogens, thereby protecting plants from further infection (Dangl and Jones, 2001; Poland et al., 2009). The gene discussed is NLRP6; the disease is infection.