Advanced tumor T stage (HR: 7.3, P = 0.007), regional lymph node metastasis (HR: 10.6, P = 0.003), distant metastasis (HR: 17.2, P < 0.001), ISUP grade (HR: 0.2, P = 0.030) and positive PD-L1 expression (HR: 6.7, P = 0.003) were associated with shorter OS. Here, CD274 is linked to neoplasm.