Investigation of neutrophil chemoattractant expression revealed that while a number of these molecules, including Cxcl1/KC, were expressed at a higher level in the heart after MI, only a subset, including Cxcl2 and Cxcl5, IL-1 and Il-6 were further increased in hearts from Hsd11b1−/− mice. Here, IL6 is linked to myocardial infarction.