The comparative analysis of immunofluorescence results obtained from particulartumours (G113, G114 and G116) cultured as three experimental models (10%adh, 0% sph, 0% adh) revealed the presence of selected CSCsmarkers (SOX2, nestin and CD44) in G113 and G116 tumour-derived cells. This evidence concerns the gene SOX2 and neoplasm.