SLC5A2 and type 2 diabetes mellitus: Using data from multiple countries in the CVD-REAL study (Comparative Effectiveness of Cardiovascular Outcomes in New Users of SGLT-2 Inhibitors: NCT02993614), we compared the risk for HHF, death, and the combined end point of HHF or death in patients with T2D who were new users of SGLT-2i versus oGLDs in real-world practice.