Some studies have reported that 5azadC induces a decrease in AP-1 expression in bone marrow mononuclear cells [36], an increase in CEBPα but a decrease in CEBPγ expression in acute myeloid leukemia cells [37] and an increase in CEBPα expression in three HPV-negative head and neck squamous cell carcinoma cell lines [38]. The gene discussed is JUN; the disease is acute myeloid leukemia.