CD34 and acute myeloid leukemia: As shown in Figure 5c, DS alone at low doses (0.05 μM and 0.1 μM) significantly reduced the number of CFU of primary CD34+ AML cells after cultured for 10–14 days (P<0.05 and P<0.01 for 0.05 μM and 0.1 μM versus untreated control, respectively), whereas combined treatment with DS and Cu (1 μM) further reduced the number of CFU (P<0.01 versus untreated control in all cases).