BIRC5 and endometrium neoplasm: A similar association has been detected in endometrial tumors where DNA methylation is related to inhibition of p53-mediated repression of survivin.20 Nevertheless, we found that survivin promoter hypermethylation in obese-derived hASCs was accompanied by a significant decrease in the levels of its mRNA (Figure 3b), indicating that additional regulatory mechanisms should exist to explain the high levels of survivin protein in hASCs from obese subjects.