EZH2 and neoplasm: It was shown that miR-101 can sensitize tumor cells chemotherapeutic drug-induced apoptosis by indirectly upregulating Bim expression in an EZH2-dependent epigenetic control manner.27 However, we demonstrated that miR-101-3p directly targets the 3′-UTR of Bim mRNA, resulting in increased Bim expression in serum-deprived endothelial cells.