ASXL2 and leukemia: Expression of WT ASXL2 cDNA or cDNA constructs bearing leukemia-associated mutant forms of ASXL2 revealed reduced stability of mutant ASXL2 relative to WT ASXL2, with greater loss of mutant ASXL2 following cycloheximide exposure (Supplementary Fig. 1a,b).