FAM20A and amelogenesis imperfecta type 1G: AI associated with gingival fibromatosis (AIGF MIM#614253; O'Sullivan et al., 2011) or enamel renal syndrome (ERS, MIM#204690; Jaureguiberry et al., 2012; Cabral et al., 2013; Wang et al., 2014; Jaouad et al., 2015; Poulter et al., 2015; Volodarsky et al., 2015) arise due to mutation of one same FAM20A gene (Jaureguiberry et al., 2012; Vogel et al., 2012; Chaitanya et al., 2014; de la Dure-Molla et al., 2014; Bhesania et al., 2015).