BST1 and major depressive disorder: In CD157 KO mice, the antidepressant-like effects of selegiline at 10 mg/kg had a tendency to be more potent than those of rasagiline at 1 mg/kg (t = −1.602, P = 0.120; Figure 1C), suggesting that selegiline is probably more effective for ameliorating depression in PD patients than rasagiline at doses that are therapeutically effective for the motor symptoms of PD.