CD157/BST-1 is also involved in the pathogenesis of several diseases such as survival of B lymphocytes in rheumatoid arthritis, progression of leukemia, and metastasis of human ovarian carcinoma cells (Kaisho et al., 1994; Shimaoka et al., 1998; Ishihara and Hirano, 2000; Ortolan et al., 2010; Quarona et al., 2013; Lo Buono et al., 2014). Here, BST1 is linked to leukemia.