In CD157 KO mice, the antidepressant-like effects of selegiline at 10 mg/kg had a tendency to be more potent than those of rasagiline at 1 mg/kg (t = −1.602, P = 0.120; Figure 1C), suggesting that selegiline is probably more effective for ameliorating depression in PD patients than rasagiline at doses that are therapeutically effective for the motor symptoms of PD. The gene discussed is BST1; the disease is Parkinson disease.