TCF21 and lung adenocarcinoma: Using the comprehensive Kaplan-Meier survival analysis platform, we discovered that decreased mRNA expression of TCF21 is an unfavorable prognostic factor of overall survival for patients with lung adenocarcinoma (hazard ratio, HR = 0.50; 95% confidence interval, 95% CI: 0.39–0.65; P = 4.7e−08; n = 673) (Fig. 6a).