CAV1 and cancer: Our study, demonstrating a role for stromal CAV1 expression in disease-free and overall survival for patients with resected CRLM, adds to the growing body of evidence supporting the prognostic value of stromal CAV1 expression in perhaps all types of malignancies, and the utility of stromal CAV1 expression but not of cancer cell CAV1 expression for the classification of cancer patients into high- and low-risk groups for recurrence and cancer-related death.