Of note, also the expression levels of other putative tumor-derived cachexia-inducing signaling compounds (OSM, LIF, TNFα, IFNγ, PTHrP, ZAG, PIF, TWEAK, IL-1β, MSTN and INHBA) were tested for possible correlation between expression level and prognosis for lung cancer patients. This evidence concerns the gene MSTN and neoplasm.