Consistent with previous reports29, 30, the serum levels of IL-6 are low in the cancer patient sera (ranging from 0.6 pg/ml to 29.3 pg/ml [Supplementary Table S3]), but associated with CRP levels; for every 10 pg/ml increase in IL-6 the estimated increase in CRP was 0.92 mg/L (Pearson chi-square, p = 9.1e-9, n = 45, 95% CI 0.66–1.2 mg/L). This evidence concerns the gene IL6 and cancer.