In addition, AGEN-T2DM conducted a meta-analysis including approximately 55,000 individuals in East Asian populations and identified eight novel T2DM loci in European populations: MAEA, FITM2-R3HDML-HNF4A, GCC1-PAX4, GLIS3, KCNK16, PEPD, PSMD6 and ZFAND3 [51]. This evidence concerns the gene PEPD and type 2 diabetes mellitus.