One of the first GWASs included 355 HBV carriers with HCC and 360 asymptomatic HBV carriers (ASCs) in Chinese population, indicated rs17401966 in KIF1B was significantly associated with HBV-related HCC, and SNPs in UBE4B and PGD genes were also shown to be significant for HCC emergence among patients with HBV-positive [64]. The gene discussed is PGD; the disease is hepatocellular carcinoma.