MAPK8 and glioblastoma: We next assessed the therapeutic relevance of dual β1 integrin/JNK targeting in an orthotopic mouse model using GS-8 GBM stem-like cells expressing EGFP and firefly luciferase (GS-8_GFP/fLuc), which had engrafted and recruited vasculature at the time of treatment (Figure 3A–3C, data not shown).