From the human genetic studies, it is known that the polymorphisms in the TNFAIP3 gene may associate with the susceptibility of multiple autoimmune diseases,[9] including systemic lupus erythematosus (SLE),[10,11] rheumatoid arthritis (RA),[12,13] psoriasis,[14] Crohn disease,[15] as well as other autoimmune diseases.[9,15] But to our knowledge, there is no report on the association of TNFAIP3 genetic polymorphisms with the MG disease. This evidence concerns the gene TNFAIP3 and autoimmune disease.