Due to its little attention paid to such other factors as age and medical history, and less data about the effect of regulation of miR-130a and GAX gene on normal cells in our study, which are likely to affect the outcomes, future studies with larger sample size are needed to provide deep investigation about how miR-130a functions on the OSAHS-associated PHT, and more advanced technology will be used to overcome those limitations. This evidence concerns the gene MEOX2 and pulmonary hypertension, primary, 1.