The evidence also showed that the GAX gene was a key point in VSMCs proliferation and migration.[24] Moreover, PHT is defined by pulmonary arteriolar remodeling with massive pulmonary VSMC proliferation.[25] However, the correlations among miRNAs, GAX gene, and OSAHS-associated PHT have not been reported yet. This evidence concerns the gene MEOX2 and obstructive sleep apnea syndrome.