Cav‐1 knockdown does not alter hydrogen peroxide‐induced premature senescence in HDFs, induces a senescence‐like morphological change, including increased cell size and formation of stress fibers in human endothelial cells, and prevents in vitro and in vivo cellular growth in human colorectal cancer cells (Chretien et al., 2008; Ha et al., 2012; Madaro et al., 2013). This evidence concerns the gene CAV1 and colorectal cancer.