Disease classes represented by this gene set (haematological, immune and infection) support this conclusion, and suggest that zinc can regulate not only hepatic immunity (IRF9, TLR7, STAT1), but immune cell migration (CXCL10, CCL19, CCL21), adhesion (COL1A1, COL3A1, COL4A1, ITGA2, ITGB5) and activation (HLA-A, HLA-B, HLA-H). The gene discussed is COL3A1; the disease is infection.