In particular, in ovarian cancer, Kulbe et al. [46] showed that in mice, TNF-α secretion by EOC cells stimulates a constitutive network consisting of cytokines (including IL-6 showed in Figure S1), chemokines, and angiogenic factors, which promotes colonization of the peritoneum and neovascularization for the development of tumor implants. The gene discussed is IL6; the disease is ovarian carcinoma.