TGFB1 and pneumonitis: –Effective in mitigating radiation-induced pneumonitis.–Trails on rats showed variable success.–Limited efficacy in human subjects. Ex: enalapril.–Certain conditions like bilateral renal artery stenosis required to be ruled out before initiation of therapy. Blood pressure should be in control.–Acts by decreasing vascular remodeling and levels of transforming growth factor β (TGF-β).