At baseline, G0F was the only IgG1 glycoform that was positively correlated with levels of ALT (Fig. 3A) and liver necroinflammation/liver fibrosis (Fig. 3B), and was inversely correlated with HBV viral load (Fig. 3C) and HBsAg titer (Fig. 3D) in HBeAg-positive patients; nevertheless, these linkages were not seen in HBeAg-negative patients. Here, GPT is linked to Hepatic fibrosis.