LTBP1 and Menkes disease: In a later study [28], we have shown that miR-M4-5p induces over-expression of the well-known oncogene c-Myc by targeting the latent TGF-β (transforming growth factor beta) binding protein 1 (LTBP1) and thus suppressing the TGF-β signalling pathway, providing further evidence for a direct in vivo role of a viral miRNA in MD lymphomagenesis.