Among human cells, A549 lung adenocarcinoma cells and their derivatives, long-term passaged (LTP) A549 cells that have suffered Y chromosome loss, featured a heterozygous KRASG12S mutation, while SKMEL2 skin melanoma, HT-29 colon adenocarcinoma, and HEK293T human embryonic kidney cells were KRAS wild-type (Table 1). Here, KRAS is linked to cutaneous melanoma.