Among the 27 ABPs deregulated in premalignant ADH and/or DCIS, EVL, Actin-related protein 3 (ACTR3), Actin-related protein 2/3 complex subunit 5-like protein (ARPC5L), Dystronin (DST), FH1/FH2 domain-containing protein 3 (FHOD3) and Tropomyosin beta chain (TPM2) were also deregulated in TAM-induced ER-Src cells (Fig. 3a)18. The gene discussed is DST; the disease is ductal breast carcinoma in situ.