Not unexpectedly, however, HOMA‐IR in T2D patients did not correlate with the adipose tissue expression of IL‐18R mRNA (P = 0.13) (Supplementary Fig. S1C) and IL‐18R protein (P = 0.40) (Supplementary Fig. S1D) as well as IL‐18 mRNA (P = 0.54) (Supplementary Fig. S1E) and IL‐18 protein (P = 0.32) (Supplementary Fig. S1F). Here, IL18 is linked to type 2 diabetes mellitus.