However, the modest reduction of ex-Foxp3 Th2 cells in the absence of Il4ra-expressing T reg cells led to a significant reduction of airway eosinophils (Fig. 6 M), suggesting that Il4ra-dependent ex-Foxp3 Th2 cells contribute HDM-driven airway eosinophilia. Here, IL4R is linked to Increased total eosinophil count.