Since MK2 is activated under various stress conditions that stimulate p38 (Cargnello and Roux, 2011), such as UV irradiation, heat shock, oxidative stress, hyperosmolarity, bacterial infection, and different cytokines, it is tempting to speculate that MK2 regulates RIPK1 under many of these stress conditions. The gene discussed is MAPKAPK2; the disease is bacterial infectious disease.