Previously, we reported that serum TG levels dramatically increase with age in Apc-deficient mice, including Min mice, and both hyperlipidemia and polyp formation were suppressed by administration of peroxisome proliferator-activated receptor (PPAR) γ ligands, suggesting that hyperlipidemia in Min mice may be associated with intestinal lesion development [34]. The gene discussed is APC; the disease is hyperlipidemia.