As Sox2 regulates SNAI2 expression via miR-452, we next tested whether high VEGFA expression (top quartile) alone or in combination with high SOX2, high SNAI2 and the lowest quartile GABRE/miR-452 expression was associated with distant metastasis-free breast cancer survival (DMFS) in the KM Plotter data set. Here, SOX2 is linked to breast cancer.