First, expression levels of Mint3 and its related proteins were examined in NFs and CAFs isolated from normal and human breast cancer tissues from the same patient.37, 38 Mint3 and FIH-1 were expressed at comparable levels in NFs and CAFs, but L1CAM and MT1-MMP expression levels increased in CAFs (Figure 6a). Here, L1CAM is linked to breast carcinoma.