CXCR4 and familial pancreatic carcinoma: Prior studies in several cell types have already identified the CXCR3-A splice variant to be responsible for cell migration.11 Our observation that CXCR3 is particularly expressed by tumor cells at the invasive front has been described for other chemokine receptors as well, such as CXCR4 in colorectal and pancreatic cancer.40, 41