PTGS2 and benign prostatic hyperplasia: In another report, flavocoxid, a flavonoid from Scutellaria baicalensis (Chinese skullcap) and Acacia catechu (black catechu), respectively, was reported to demonstrate anti-BPH properties and the mechanism of action was reported to involve decreasing growth factor expression and inhibition of COX-2 and 5-lipoxygenase activities in the prostatic tissue of BPH rats (Altavilla et al., 2012).