Regarding TNF rs1799964 polymorphism, significantly higher frequency of heterozygous TC genotype was observed in infants with congenital CMV infection than in the control group (OR = 2.15; 95% CI, 1.27–3.63; p = 0.005 and OR = 2.17; 95% CI, 1.25–3.77; p = 0.007, for unadjusted and adjusted regression model, respectively). The gene discussed is TNF; the disease is cytomegalovirus infection.