The Ile923Val allele has been previously reported to be protective for type 1 diabetes18 and psoriasis.19 Associations within the IFIH1 locus have also been reported to increase PsA risk.10 20 However, until now no association with the Ile923Val allele has been reported to have a protective effect on PsA alone. The gene discussed is IFIH1; the disease is psoriasis.