The single-trait BP meta-analyses identified several genome-wide significant single nucleotide polymorphisms (SNP) at eight loci (P < 5.0×10−8, systolic BP (SBP): three loci, four SNPs; diastolic BP (DBP): three loci, three SNPs; pulse pressure (PP): three loci, four SNPs; and hypertension (HTN): one locus, one SNP), with the EVX1/HOXA locus identified for SBP, DBP and HTN (S2A–S2D Fig). This evidence concerns the gene EVX1 and hypertensive disorder.