SLC2A1 and neoplasm: As shown in Figure 3, overexpression of GLUT1 was identified to be significantly associated with poor differentiated tumors (RR = 1.380, 95% CI = 1.086 – 1.755, p = 0.009; I2 = 72.0%, p < 0.001) (Figure 3A), positive lymph node metastasis (RR = 1.395, 95% CI = 1.082–1.799, p = 0.010; I2 = 70.8%, p = 0.002) (Figure 3B) and larger tumor size (RR = 1.405, 95% CI = 1.231 – 1.603, p < 0.001; I2 = 37.3%, p = 0.093) (Figure 3C).