The only significant difference found between subjects with and without recurrence was age (p = 0.04), while gender, presence of cirrhosis, levels of α-feto protein (AFP), Aspartate aminotransferase (AST), and Alanine transaminase (ALT), tumor size, margin-free width, tumor grading, satellitosis, capsular invasion, microvascular invasion, and percentage of Ki67-positive cells did not show statistically significant association with tumor recurrence. The gene discussed is AFP; the disease is neoplasm.