In the evaluation of BChE activity, obesity is a major condition to be considered, sinceseveral studies showed that obese individuals tend to have increased activity of thisenzyme as a result of increased levels of choline esters, which are products of freefatty acid metabolism and hepatic lipogenesis, and both metabolic traits are alteredwith obesity (Alcântara et al.,2005; Randell et al.,2005; Furtado-Alle et al.,2008). The gene discussed is BCHE; the disease is Obesity.