PTEN and glioblastoma: However, no significant changes in DAXX protein signal were observed within PTEN-positive and PTEN-negative adult GBM samples (Fig. 6c, Chi-square 0.7639, P=0.6825, n=68); but a significant anticorrelated expression (cor=−0.298, P=0.001, n=166) between DAXX and PTEN-WT was found in the GBM-TCGA database (Fig. 6d) and confirmed by immunohistochemistry in adult GBM tissues (Fig. 6e, cor=−0.3721 P=0.0025, n=67).