PTEN and glioblastoma: Imaging using fluorescence molecular tomography showed a decrease in fluorescence signal in mice engrafted with shDAXX/PTEN-deficient (GSC11, GSC23, HK281) GBM neurospheres in comparison with animals implanted with shDAXX/PTEN-WT (TS576, GBM39, GBM6, TS543) GBM cells (Fig. 5a,b, Supplementary Fig. 16c,d).