PMEL and neoplasm: Similarly, a long-term follow-up of the NCI trial also revealed “durable” and “potentially curative tumor regressions” in melanoma with the combinations of Ipilimumab and IL-2 or Ipilimumab and gp100 (5-year survival rates of 25 and 23%, respectively, while the same with Ipilimumab alone being 13%) [43].