HSPB1 and non-small cell lung carcinoma: It was reported in studies of patients treated with RT for non-small-cell lung cancer (NSCLC) that the HSPB1 rs2868371 SNP was associated with grade 3 or greater radiation pneumonitis (31) in both the training (p = 0.031) and validation sets (p = 0.025) and that this SNP was also associated with the development of grade 3 or greater radiation-induced esophagitis (32) in both the training (p = 0.045) and validation cohorts (p = 0.031).