Thereafter, amounts of studies found in both animal disease model and diabetic population that type 2 diabetes is accompanied by the elevation of blood lipopolysaccharides (LPS), C-reactive protein (CRP), interleukin (IL)-6, and IL-1, etc. (Yudkin et al., 1999; Cani et al., 2007a; Zhao et al., 2012), further confirmed the low-grade inflammation nature of diabetes. Here, CRP is linked to diabetes mellitus.