Those genes are consistent with their activation state and the upregulation of carcinogenic processes, as it can be observed in Fig. 5, where the majority molecules expression values were in agreement to the exacerbated levels of cancer-related pathways, e.g. overexpression of KDM5B, an important oncogene in breast cancer40, 41, IQGAP3, CCNB1, CDK1 or CCNE2, which are highly involved in the correct function of cell cycle checkpoints and promotion of cell division. The gene discussed is IQGAP3; the disease is cancer.