Indeed, other ligands, which have been involved in metabolic disorders, can modulate ERBB phosphorylation state25, such as NRG426, 27, betacellulin28, 29, epiregulin30 or proheparin-binding EGF-like growth factor (HB-EGF)31, 32. The gene discussed is GSTM1; the disease is Other metabolic disease.